Ontology highlight
ABSTRACT:
SUBMITTER: Tellez-Gabriel M
PROVIDER: S-EPMC9047906 | biostudies-literature | 2022
REPOSITORIES: biostudies-literature
Tellez-Gabriel Marta M Tekpli Xavier X Reine Trine M TM Hegge Beate B Nielsen Stephanie R SR Chen Meng M Moi Line L Normann Lisa Svartdal LS Busund Lill-Tove R LR Calin George A GA Mælandsmo Gunhild M GM Perander Maria M Theocharis Achilleas D AD Kolset Svein O SO Knutsen Erik E
Frontiers in oncology 20220414
Serglycin is a proteoglycan highly expressed by immune cells, in which its functions are linked to storage, secretion, transport, and protection of chemokines, proteases, histamine, growth factors, and other bioactive molecules. In recent years, it has been demonstrated that serglycin is also expressed by several other cell types, such as endothelial cells, muscle cells, and multiple types of cancer cells. Here, we show that serglycin expression is upregulated in transforming growth factor beta ...[more]