Phylogenetic Distribution and Evolution of Type VI Secretion System in the Genus Xanthomonas.

ABSTRACT: The type VI secretion system (T6SS) present in many Gram-negative bacteria is a contact-dependent apparatus that can directly deliver secreted effectors or toxins into diverse neighboring cellular targets including both prokaryotic and eukaryotic organisms. Recent reverse genetics studies with T6 core gene loci have indicated the importance of functional T6SS toward overall competitive fitness in various pathogenic Xanthomonas spp. To understand the contribution of T6SS toward ecology and evolution of Xanthomonas spp., we explored the distribution of the three distinguishable T6SS clusters, i3*, i3***, and i4, in approximately 1,740 Xanthomonas genomes, along with their conservation, genetic organization, and their evolutionary patterns in this genus. Screening genomes

SUBMITTER: Liyanapathiranage P 

PROVIDER: S-EPMC9048695 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature