Phytochemistry by design: a case study of the chemical composition of Ocotea guianensis optimized extracts focused on untargeted metabolomics analysis.

ABSTRACT: Untargeted metabolomics aim to provide a global chemical fingerprint of biological matrices. This research field can be used in phytochemical screenings for bioactive species or in the identification of species. Despite its importance in providing a global chemical profile, little research has focused on the optimization of the extraction methods, as each type of matrix requires a specific procedure. Therefore, we propose to evaluate the effect of different extraction features in an ultrasound-assisted extraction for the untargeted metabolomic study of an Ocotea species, a genus of great economical interest but little chemical exploitation. Method optimization was performed in a full factorial 2²3² design, evaluating the solvent composition, extraction temperat

SUBMITTER: Antonio ADS 

PROVIDER: S-EPMC9048970 | biostudies-literature | 2020 Jan

REPOSITORIES: biostudies-literature