Suggested Sustainable Medical and Environmental Uses of Melanin Pigment From Halotolerant Black Yeast Hortaea werneckii AS1.

ABSTRACT: The marine ecosystem is a complex niche with unique environmental circumstances. Microbial communities from the sea are one of the main origins of compounds with tremendous capabilities. Marine yeasts have the ability to produce secondary metabolites that are architecturally distinct from those found in terrestrial species. Melanin pigment synthesized by marine halotolerant black yeast Hortaea werneckii AS1 isolated from Mediterranean salt lakes in Alexandria, Egypt was found to exert a radical scavenging effect on 2,2-diphenyl-1-picrylhydrazyl (DPPH) with an IC₅₀ of 61.38 μg/ml. Furthermore, it showed no cytotoxicity toward human skin fibroblast cell line (HSF) with an IC₅₀ value above 0.1 mg/ml. The antimicrobial capability of the pigment was revealed against

SUBMITTER: Elsayis A 

PROVIDER: S-EPMC9048979 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature