Molecular docking analysis of p53 with Toll-like receptors.

ABSTRACT: P53 is one of the most important proteins for its role in cellular signal transduction pathways. It regulates a wide variety of cellular processes, which includes apoptosis, senescence, cell cycle arrest, differentiation, and DNA repair and replication and cancer dynamics. It is a transcription factor for various cellular proteins. Recent report suggests that P53 is linked with transduction proteins involved in cellular immunity. Toll like receptors are needed for communication in cellular immunity. The interaction between p53 and toll like receptors is reported in various studies. Therefore, it is of interest to document the molecular docking analysis of p53 with Toll-like receptors for further consideration in therapeutic development. In the present paper we studied molecular interaction

SUBMITTER: Alam MJ 

PROVIDER: S-EPMC9049089 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature