A novel cerium(iii)-isatin Schiff base complex: spectrofluorometric and DFT studies and application as a kidney biomarker for ultrasensitive detection of human creatinine.

ABSTRACT: In this paper, a new isatin-Schiff base L1 was prepared via a simple reaction of isatin with 2-amino-3-hydroxypyridin. Subsequently, cerium(iii)-Schiff base complex C1 was obtained through the reaction of the prepared Schiff base L1 with cerium chloride via a hydrothermal method. The prepared L1, as well as C1, were fully characterized using many spectroscopic techniques, such as mass spectra, elemental analysis, UV-vis, FT-IR, ¹H-NMR, ¹³C-NMR, FE-SEM/EDX, and HR-TEM. A photoluminescence study (PL) was carried out for the prepared complex C1. The promising photoluminescence results revealed that C1 could be used for the detection of creatinine in different human biological samples as a selective optical biosensor. The results showed that C1 after excitat

SUBMITTER: Sheta SM 

PROVIDER: S-EPMC9049238 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature