Association of Adverse Events With Antibiotic Treatment for Urinary Tract Infection.

ABSTRACT:

Background

Little is known about the relative harms of different antibiotic regimens prescribed to treat uncomplicated urinary tract infection (UTI). We sought to compare the risk of adverse events associated with commonly used oral antibiotic regimens for the outpatient treatment of uncomplicated UTI.

Methods

Using data from the IBM® MarketScan® Commercial Database, we identified 1 169 033 otherwise healthy, nonpregnant women aged 18-44 years with uncomplicated UTI who initiated an oral antibiotic with activity against common uropathogens from 1 July 2006 to 30 September 2015. We used propensity score-weighted Kaplan-Meier methods and Cox proportional hazards regression models to estimate the association between antibiotic agent and adverse events.

Results

Of 2 first

SUBMITTER: Butler AM 

PROVIDER: S-EPMC9049277 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature