Novel amphiphilic graft block azobenzene-containing copolymer with polypeptide block: synthesis, self-assembly and photo-responsive behavior.

ABSTRACT: Well-defined amphiphilic graft block azobenzene-containing copolymer with polypeptide block was synthesized via a combination of copper-mediated atom transfer radical polymerization (ATRP), ring-opening polymerization and click reaction. The alkyne-terminated poly[6-(4-methoxy-azobenzene-4'-oxy)hexyl methacrylate] (PAzoMA) was synthesized by ATRP with a bromine-containing alkyne bifunctional initiator, and the azido-terminated poly(γ-2-chloroethyl-l-glutamate) (PCELG) was synthesized by ROP of γ-2-chloroethyl-l-glutamate-N-carboxyanhydride (CELG-NCA), then the two homopolymers were conjugated by click reaction to afford block azobenzene-containing copolymer PAzoMA-b-PCELG. The chloro groups in PCELG block were transformed into azido groups via azide reactions, a

SUBMITTER: He X 

PROVIDER: S-EPMC9049285 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature