An updated overview on the regulatory circuits of polyhydroxyalkanoates synthesis.

ABSTRACT: Polyhydroxyalkanoates (PHA) are a promising and sustainable alternative to the petroleum-based synthetic plastics. Regulation of PHA synthesis is receiving considerable importance as engineering the regulatory factors might help developing strains with improved PHA-producing abilities. PHA synthesis is dedicatedly regulated by a number of regulatory networks. They tightly control the PHA content, granule size and their distribution in cells. Most PHA-accumulating microorganisms have multiple regulatory networks that impart a combined effect on PHA metabolism. Among them, several factors ranging from global to specific regulators, have been identified and characterized till now. This review is an attempt to categorically summarize the diverse regulatory circuits that operate in some importa

SUBMITTER: Mitra R 

PROVIDER: S-EPMC9049629 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature