Classical-Contextual Interactions in V1 May Rely on Dendritic Computations.

ABSTRACT: A signature feature of the neocortex is the dense network of horizontal connections (HCs) through which pyramidal neurons (PNs) exchange "contextual" information. In primary visual cortex (V1), HCs are thought to facilitate boundary detection, a crucial operation for object recognition, but how HCs modulate PN responses to boundary cues within their classical receptive fields (CRF) remains unknown. We began by "asking" natural images, through a structured data collection and ground truth labeling process, what function a V1 cell should use to compute boundary probability from aligned edge cues within and outside its CRF. The "answer" was an asymmetric 2-D sigmoidal function, whose nonlinear form provides the first normative account for the "multiplicative" center-flanker interactions previ

SUBMITTER: Jin L 

PROVIDER: S-EPMC9049952 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature