Task-related hemodynamic responses in human early visual cortex are modulated by task difficulty and behavioral performance.

ABSTRACT: Early visual cortex exhibits widespread hemodynamic responses in the absence of visual stimulation, which are entrained to the timing of a task and not predicted by local spiking or local field potential. Such task-related responses (TRRs) covary with reward magnitude and physiological signatures of arousal. It is unknown, however, if TRRs change on a trial-to-trial basis according to behavioral performance and task difficulty. If so, this would suggest that TRRs reflect arousal on a trial-to-trial timescale and covary with critical task and behavioral variables. We measured functional magnetic resonance imaging blood-oxygen-level-dependent (fMRI-BOLD) responses in the early visual cortex of human observers performing an orientation discrimination task consisting of separate easy and hard

SUBMITTER: Burlingham CS 

PROVIDER: S-EPMC9049970 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature