Iodine-catalyzed convergent aerobic dehydro-aromatization toward benzazoles and benzazines.

ABSTRACT: An iodine-catalyzed aerobic dehydro-aromatization has been developed, providing straightforward and efficient access to various benzoazoles and benzoazines. The present transition-metal-free protocol enables the dehydro-aromatization of tetrahydrobenzazoles and tetrahydroquinolines with molecular oxygen as the green oxidant, along with some other N-heterocycles. Hence, a broad range of heteroaromatic compounds are generated in moderate to good yields under facile reaction conditions.

SUBMITTER: Tuo X 

PROVIDER: S-EPMC9049994 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature