An efficient method to obtain anti-inflammatory phenolic derivatives from Scindapsus officinalis (Roxb.) Schott. by a high speed counter-current chromatography coupled with a recycling mode.

ABSTRACT: Herein, we provide an effective separation strategy based on liquid-liquid extraction and two different modes of high speed counter-current chromatography (HSCCC) for the rapid enrichment and separation of compounds from n-butanol-partitioned samples of S. officinalis. Liquid-liquid extraction of the crude sample was performed using a two-phase solvent system composed of ethyl acetate-n-butanol-water with volume ratios of 9 : 0 : 9, 5 : 4 : 9 and 3 : 6 : 9 (v/v), which allowed components with lower polarity and higher polarity to be enriched separately with the first ratio and the other two ratios, respectively. For separation, the conventional and recycling mode HSCCC were combined to develop a strategy for the acquisition of eight phenolic derivatives from the enrich

SUBMITTER: Yu J 

PROVIDER: S-EPMC9050415 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature