Chemiluminescent organic nanophotosensitizer for a penetration depth independent photodynamic therapy.

ABSTRACT: Photodynamic therapy initiated by external photoexcitation is a clinically-approved therapeutic paradigm, but its practical application has been severely hindered by the shallow penetration of light. Here, we describe a penetration-independent PDT modality using a chemiluminescent organic nanophotosensitizer, which is activated by hydrogen peroxide instead of external photoexcitation.

SUBMITTER: Lu X 

PROVIDER: S-EPMC9050500 | biostudies-literature | 2020 Mar

REPOSITORIES: biostudies-literature