Incorrect application of the KDIGO acute kidney injury staging criteria.

ABSTRACT:

Background

Recent research demonstrated substantial heterogeneity in the Kidney Disease: Improving Global Outcomes (KDIGO) acute kidney injury (AKI) diagnosis and staging criteria implementations in clinical research. Here we report an additional issue in the implementation of the criteria: the incorrect description and application of a stage 3 serum creatinine (SCr) criterion. Instead of an increase in SCr to or beyond 4.0 mg/dL, studies apparently interpreted this criterion as an increase in SCr by 4.0 mg/dL.

Methods

Using a sample of 8124 consecutive intensive care unit (ICU) admissions, we illustrate the implications of such incorrect application. The AKI stage distributions associated with the correct and incorrect stage 3 SCr criterion implementations were compared, bo

SUBMITTER: Yasrebi-de Kom IAR 

PROVIDER: S-EPMC9050561 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature