Evaluation of corneal nerves and dendritic cells by in vivo confocal microscopy after Descemet's membrane keratoplasty for bullous keratopathy.

ABSTRACT: This study evaluated changes in corneal nerves and the number of dendritic cells (DCs) in corneal basal epithelium following Descemet membrane endothelial keratoplasty (DMEK) surgery for bullous keratopathy (BK). Twenty-three eyes from 16 consecutive patients that underwent DMEK for BK were included. Eyes of age-matched patients that underwent pre-cataract surgery (12 eyes) were used as controls. In vivo confocal microscopy was performed pre- and postoperatively at 6, 12, and 24 months. Corneal nerve length, corneal nerve trunks, number of branches, and the number of DCs were determined. The total corneal nerve length of 1634.7 ± 1389.1 μm/mm² before surgery was significantly increased in a time-dependent manner to 4485.8 ± 1403.7 μm/mm², 6949.5 ± 1477.1 μm/mm^2</

SUBMITTER: Shimizu T 

PROVIDER: S-EPMC9050645 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature