Learning from COVID-19 related trial adaptations to inform efficient trial design-a sequential mixed methods study.

ABSTRACT:

Background

Many clinical trial procedures were often undertaken in-person prior to the COVID-19 pandemic, which has resulted in adaptations to these procedures to enable trials to continue. The aim of this study was to understand whether the adaptations made to clinical trials by UK Clinical Trials Units (CTUs) during the pandemic have the potential to improve the efficiency of trials post-pandemic.

Methods

This was a mixed methods study, initially involving an online survey administered to all registered UK CTUs to identify studies that had made adaptations due to the pandemic. Representatives from selected studies were qualitatively interviewed to explore the adaptations made and their potential to improve the efficiency of future trials. A literature review was undertaken

SUBMITTER: Chatters R 

PROVIDER: S-EPMC9051017 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature