Novel synthesis of divergent aryl imidazoles from ketones involving copper-catalyzed α-amination and oxidative C-C bond cleavage.

ABSTRACT: A one-pot synthesis, initiated by a copper salt with inorganic (NH₄)₂CO₃ as the nitrogen source, forms divergent aryl imidazole derivatives from ketones via α-amination and oxidative C-C bond cleavage reactions. The approach provides a simple and rapid synthesis of imidazole derivatives and has certain versatility.

SUBMITTER: Huang J 

PROVIDER: S-EPMC9051655 | biostudies-literature | 2020 Apr

REPOSITORIES: biostudies-literature