Diagnostic value of integrated ¹⁸F-PSMA-1007 PET/MRI compared with that of biparametric MRI for the detection of prostate cancer.

ABSTRACT:

Objective

To assess the diagnostic value of fluorine 18 (¹⁸F)-labeled prostate-specific membrane antigen (PSMA)-1007 Positron emission tomography/Magnetic resonance imaging (PET/MRI) and compared with that of biparametric MRI (bpMRI) for the detection of prostate cancer (PCa).

Materials and methods

The study enrolled 29 patients with suspected PCa preoperatively who underwent ¹⁸F-PSMA-1007 PET/MRI and subsequent targeted biopsy for suspected PCa lesions. Two readers independently assessed the images of each suspected PCa lesion and determined their overall assessment category on bpMRI and ¹⁸F-PSMA-1007 PET/MRI. By using biopsy histopathology as the reference standard, the accuracies of ¹⁸F-PSMA-1007 PET/MRI and bpMRI for the detect

SUBMITTER: Zeng Y 

PROVIDER: S-EPMC9052074 | biostudies-literature | 2022 Jun

REPOSITORIES: biostudies-literature