Aging metrics incorporating cognitive and physical function capture mortality risk: results from two prospective cohort studies.

ABSTRACT:

Background

Aging metrics incorporating cognitive and physical function are not fully understood, hampering their utility in research and clinical practice. This study aimed to determine the proportions of vulnerable persons identified by three existing aging metrics that incorporate cognitive and physical function and the associations of the three metrics with mortality.

Methods

We considered three existing aging metrics including the combined presence of cognitive impairment and physical frailty (CI-PF), the frailty index (FI), and the motoric cognitive risk syndrome (MCR). We operationalized them using data from the China Health and Retirement Longitudinal Study (CHARLS) and the US National Health and Nutrition Examination Survey (NHANES). Logistic regression models or Cox

SUBMITTER: Cao X 

PROVIDER: S-EPMC9052591 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature