Long-term relative survival in uveal melanoma: a systematic review and meta-analysis.

ABSTRACT:

Background

A large proportion of patients with uveal melanoma develop metastases and succumb to their disease. Reports on the size of this proportion vary considerably.

Methods

PubMed, Web of Science and Embase were searched for articles published after 1980. Studies with ≥100 patients reporting ≥five-year relative survival rates were included. Studies solely reporting Kaplan-Meier estimates and cumulative incidences were not considered, due to risk for competing risk bias and classification errors. A meta-analysis was performed using random-effects and weighted averages models, as well as a combined estimate based on curve fitting.

Results

Nine studies and a total of 18 495 patients are included. Overall, the risk of selective reporting bias is low. Relative survival

SUBMITTER: Stalhammar G 

PROVIDER: S-EPMC9053233 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature