Adherence and sustainability of interventions informing optimal control against the COVID-19 pandemic.

ABSTRACT:

Background

After one year of stop-and-go COVID-19 mitigation, in the spring of 2021 European countries still experienced sustained viral circulation due to the Alpha variant. As the prospect of entering a new pandemic phase through vaccination was drawing closer, a key challenge remained on how to balance the efficacy of long-lasting interventions and their impact on the quality of life.

Methods

Focusing on the third wave in France during spring 2021, we simulate intervention scenarios of varying intensity and duration, with potential waning of adherence over time, based on past mobility data and modeling estimates. We identify optimal strategies by balancing efficacy of interventions with a data-driven "distress" index, integrating intensity and duration of social distancin

SUBMITTER: Di Domenico L 

PROVIDER: S-EPMC9053235 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature