Quality of life and metabolic outcomes after total pancreatectomy and simultaneous islet autotransplantation.

ABSTRACT:

Background

Pancreas surgery remains technically challenging and is associated with considerable morbidity and mortality. Identification of predictive risk factors for complications have led to a stratified surgical approach and postoperative management. The option of simultaneous islet autotransplantation (sIAT) allows for significant attenuation of long-term metabolic and overall complications and improvement of quality of life (QoL). The potential of sIAT to stratify a priori the indication for total pancreatectomy is yet not adequately evaluated.

Methods

The aim of this analysis was to evaluate the potential of sIAT in patients undergoing total pancreatectomy to improve QoL, functional and overall outcome and therefore modify the surgical strategy towards earlier and exte

SUBMITTER: Ludwig S 

PROVIDER: S-EPMC9053265 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature