Positive Correlation of Oestradiol Level on Trigger Day with the Secretion Level of Endometrial Kisspeptin and Leukaemia Inhibitory Factor in the Mid-Luteal Stimulated Cycle.

ABSTRACT:

Background

Kisspeptin plays a role in the oestradiol negative-feedback regulation of GnRH as well as gonadotropin. In addition, kisspeptin has been postulated to induce the production of an important cytokine called leukaemia inhibitory factor (LIF).

Aims

This study aims to investigate the correlation between varying oestradiol levels measured on trigger day of the ovarian stimulation and the mRNA expression level of endometrial kisspeptin and LIF.

Study setting and design

Prospective cross-sectional study took place in Morula IVF Jakarta clinic.

Materials and methods

A total of 43 infertile couples underwent an in-vitro fertilization (IVF) program. Subjects were grouped based on oestradiol levels as follows: group A ([≧ 3000 pg/mL, n = 15], group B [200

SUBMITTER: Polim AA 

PROVIDER: S-EPMC9053344 | biostudies-literature | 2022 Jan-Mar

REPOSITORIES: biostudies-literature