Chlorotrifluoroethylidenes: an efficient and convenient approach to their synthesis.

ABSTRACT: A convenient one step synthesis of chlorotrifluoroalkyl olefins starting from aldehydes was developed. The stable reagent 2-((1-chloro-2,2,2-trifluoroethyl)sulfonyl)benzothiazole was prepared from readily available benzothiazole-2-thiol and halothane. This method comprises using stable 2-((1-chloro-2,2,2-trifluoroethyl)sulfonyl)benzothiazole according to the Julia procedure and presents new opportunities for the synthesis of trifluoroalkylidene derivatives.

SUBMITTER: Upare AA 

PROVIDER: S-EPMC9053503 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature