Chronobiological Patterns of Aneurysmal Subarachnoid Hemorrhage in Central China.

ABSTRACT:

Background

Aneurysmal subarachnoid hemorrhage (aSAH) is an acute and sometimes fatal cerebrovascular disease. The chronobiological patterns of aSAH are still unclear worldwide. This 15-year time-series study aims to clarify the chronobiological patterns including seasonal, monthly, weekly, and circadian distributions of aSAH.

Methods

We retrospectively analyzed the medical records of aSAH patients in central China. To investigate seasonal and weekly distributions, we used the χ2 goodness-of-fit test to analyze the uniformity of the onset time. To explore monthly and circadian distributions, we established Fourier models to show the rhythmicity in chronobiological patterns. Subgroup analyses were conducted to assess the impact of age, gender, hypertension statuses, and aneury

SUBMITTER: Wu Y 

PROVIDER: S-EPMC9053527 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature