Clinical characteristics and risk factors for severe scrub typhus in pediatric and elderly patients.

ABSTRACT:

Background

Scrub typhus (ST) is a life-threatening infectious disease if appropriate treatment is unavailable. Large discrepancy of clinical severity of ST patients was reported among age groups, and the underlying risk factors for severe disease are unclear.

Methods

Clinical and epidemiological data of ST patients were collected in 55 surveillance hospitals located in Guangzhou City, China, from 2012 to 2018. Severe prognosis and related factors were determined and compared between pediatric and elderly patients.

Results

A total of 2,074 ST patients including 209 pediatric patients and 1,865 elderly patients were included, with a comparable disease severity rate of 11.0% (95% CI 7.1%-16.1%) and 10.3% (95% CI 9.0%-11.8%). Different frequencies of clinical characterist

SUBMITTER: Guan XG 

PROVIDER: S-EPMC9053809 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature