Long-acting injectable antipsychotics for early psychosis: A comprehensive systematic review.

ABSTRACT:

Aim

Long acting injectable (LAI) antipsychotics are an alternative to oral antipsychotic (OAP) treatment and may be beneficial for patients in the early stages of schizophrenia. This study aims to provide a comprehensive review on the efficacy of first-generation and second-generation LAI antipsychotics in recent-onset, first-episode, and early psychosis patients.

Methods

MEDLINE, EMBASE, PsycINFO, and Web of Science Core databases were used to search for studies that used LAIs in early psychosis patients. Studies published up to 06 Jun 2019 were included with no language restrictions applied. Inclusion criteria were a diagnosis of schizophrenia or related disorder, where patients were in their first episode or had a duration of illness ≤5 years.

Results

33 studies we

SUBMITTER: Lian L 

PROVIDER: S-EPMC9053823 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature