Phomretones A-F, C₁₂ polyketides from the co-cultivation of Phoma sp. YUD17001 and Armillaria sp.

ABSTRACT: Six new C₁₂ polyketides, phomretones A-F (1-6), were isolated from the co-culture of Armillaria sp. and the endophytic fungus Phoma sp. YUD17001 associated with Gastrodia elata. Neither fungus produced these compounds when cultured alone. The structures of 1-6 were established on the basis of comprehensive spectroscopic analyses, while their absolute configurations were determined by the comparsion of experimental and calculated ECD spectra. Compounds 2-4 are diastereoisomers of each other and featured high levels of stereoisomerization and oxidation.

SUBMITTER: Li HT 

PROVIDER: S-EPMC9053967 | biostudies-literature | 2020 May

REPOSITORIES: biostudies-literature