Sensitivity enhancement via multiple contacts in the {¹H-²⁹Si}-¹H cross polarization experiment: a case study of modified silica nanoparticle surfaces.

ABSTRACT: {¹H-²⁹Si}-¹H double cross polarization inverse detection (DCPi) solid-state NMR, has recently been shown to be a powerful tool for studying molecules adsorbed on the silica surface. In this contribution, we develop an improved version (MCPi) which incorporates a block of multiple contact pulses, and quantitatively compare the sensitivities of MCPi and DCPi over a typical range of experimental parameters. The MCPi pulse sequence aims at higher sensitivity and robustness for studying samples with various relaxation characteristics. In the case of dimethyl sulfoxide (DMSO) molecules adsorbed on the silica surface, MCPi performs equally well or up to 2.5 times better than DCPi over a wide range of parameters. The applicability to and performance of MCPi on comp

SUBMITTER: Yan C 

PROVIDER: S-EPMC9054631 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature