Biguanide-transition metals complexes as potential drug for hyperglycemia treatment.

ABSTRACT: Coordination compounds of Cu(ii), Ni(ii), Co(ii), and Zn(ii) with a type of biguanide (known commercially as metformin) have been synthesized and characterized using spectroscopic techniques (FT-IR, UV/VIS), X-ray diffraction techniques and thermal analysis. For all compounds, single crystals were obtained for single-crystal X-ray diffraction. For the first time, an octahedral cobalt compound with the formula [Co(C₄H₁₁N₅)₃]Cl₂·2H₂O that crystallizes in the monoclinic space group C2/c with one molecule in the asymmetric unit has been obtained. Also, a novel nickel compound with the formula [Ni(C₄H₁₁N₅) (C₄H₁₀N₅)]Cl·H₂O that crystallizes

SUBMITTER: Villamizar-Delgado S 

PROVIDER: S-EPMC9054726 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature