Nanoengineering the surface of corneal implants: towards functional anti-microbial and biofilm materials.
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ABSTRACT:
SUBMITTER: Khatoon Z
PROVIDER: S-EPMC9054791 | biostudies-literature | 2020 Jun
REPOSITORIES: biostudies-literature
Publications
Nanoengineering the surface of corneal implants: towards functional anti-microbial and biofilm materials.
Khatoon Zohra Z Guzmán-Soto Irene I McTiernan Christopher D CD Lazurko Caitlin C Simpson Fiona F Zhang Li L Cortes David D Mah Thien-Fah TF Griffith May M Alarcon Emilio I EI
RSC advances 20200622 40
We report the development and use of a light-mediated <i>in situ</i> grafting technology for the surface modification of biosynthetic corneal implants with peptide-capped nanoparticles (15-65 nm). The resulting materials have antimicrobial properties in bacterial suspension and also reduced the extent of biofilm formation. Our <i>in situ</i> grafting technology offers a rapid route for the introduction of antimicrobial properties to premoulded corneal implants, and potentially other soft implant ...[more]
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