Removal of the A₁₀ adenosine in a DNA-stabilized Ag₁₆ nanocluster.

ABSTRACT: The role of the terminal adenosine (A₁₀) on the spectroscopic and structural properties of a previously described DNA-stabilized Ag₁₆ nanocluster (DNA:Ag₁₆NC) is presented. In the original DNA:Ag₁₆NCs (5'-CACCTAGCGA-3'), the A₁₀ nucleobase was involved in an Ag⁺-mediated interaction with an A₁₀ in a neighboring asymmetric unit, and did not interact with the Ag₁₆NC. Therefore, we synthesized AgNCs embedded in the corresponding 9-base sequence in order to investigate the crystal structure of these new DNA-A₁₀:Ag₁₆NCs and analyze the photophysical properties of the solution and crystalline state. The X-ray crystallography and spectroscopic measurements revealed that the 3'-end adenosi

SUBMITTER: Cerretani C 

PROVIDER: S-EPMC9054913 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature