Development of an ultrasound-enhanced smartphone colorimetric biosensor for ultrasensitive hydrogen peroxide detection and its applications.

ABSTRACT: In this work, we developed the first ultrasound technique enhanced smartphone application for highly sensitive determination of hydrogen peroxide (H₂O₂). The measurement technique is based on the change in color intensity due to the transformation of tetramethylbenzidine (TMB) to oxidized tetramethylbenzidine (oxTMB) by the oxidation process with hydroxyl radical (OH˙) from the oxidation etching of silver nanoparticles (AgNPs) and its ultrasound usability. The oxTMB product occurs without peroxidase and can be detected with a saturation channel using HSV methodology via the application of a smartphone. To prove the peroxidase mimic property, our proposed method was also validated by determination of certain biomolecules, including glucose, uric acid, acetylchol

SUBMITTER: Khachornsakkul K 

PROVIDER: S-EPMC9055123 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature