Fabrication of an (α-Mn₂O₃:Co)-decorated CNT highly sensitive screen printed electrode for the optimization and electrochemical determination of cyclobenzaprine hydrochloride using response surface methodology.

ABSTRACT: A new chemically optimized screen-printed electrode modified with a cobalt-doped α-Mn₂O₃ nanostructure on carbon nanotube paste (α-Mn₂O₃:Co@CNTs) has been constructed for the recognition of cyclobenzaprine hydrochloride. The prepared paste is based on the incorporation of oxide ion conductors, such as the α-Mn₂O₃ nanostructure with cobalt and ion pairs (tetraphenyl borate coupled with the drug), as electroactive species in the screen-printed electrode to increase the sensor surface area and decrease electrical resistance. The central composite design is a useful methodology for the estimation and modeling of the exact optimum parameters specifically designed for this process. This is a good way to graphically clarify the rel

SUBMITTER: Abdel-Raoof AM 

PROVIDER: S-EPMC9055185 | biostudies-literature | 2020 Jun

REPOSITORIES: biostudies-literature