Doxorubicin-loaded Cu₂S/Tween-20 nanocomposites for light-triggered tumor photothermal therapy and chemotherapy.

ABSTRACT: In clinical tumor therapy, traditional treatments such as surgery, radiotherapy and chemotherapy all have their own limitations. With the development of nanotechnology, new therapeutic methods based on nanomaterials such as photothermal therapy (PTT) have also emerged. PTT takes advantage of the poor thermal tolerance of tumor cells and uses the heat generated by photothermal reagents to kill tumor cells. A transition metal sulfide represented as Cu₂S is an ideal photothermal reagent because of its easy preparation, high extinction coefficient and photothermal conversion efficiency. Surface modification of nanoparticles (NPs) is also necessary, which not only can reduce toxicity and improve colloidal stability, but also can provide the possibility of further chemotherapeutic dru

SUBMITTER: Liu S 

PROVIDER: S-EPMC9055350 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature