Effects of spermine on ileal physical barrier, antioxidant capacity, metabolic profile and large intestinal bacteria in piglets.

ABSTRACT: Spermine, a polyamine, exerts important roles in alleviating oxidative damage, improving immunity, increasing antioxidant status and digestive enzyme activities, and promoting the development of small intestine. However, information is not available regarding the effects of spermine supplementation on gut barrier function, intestinal microbiota and metabolic profile in piglets. Therefore, this study was designed to explore the effect of spermine administration on these parameters. The experiment was conducted on twenty 12 day-old suckling piglets, which were allocated either to the group fed basal formula milk (control group) or to that fed a basal formula milk that contained spermine (0.4 mmol kg^-1 BW per day) for 3 days. Caecal and colonic digesta and ileal tissues were collec

SUBMITTER: Liu G 

PROVIDER: S-EPMC9055407 | biostudies-literature | 2020 Jul

REPOSITORIES: biostudies-literature