Associations Between the Digital Clock Drawing Test and Brain Volume: Large Community-Based Prospective Cohort (Framingham Heart Study).

ABSTRACT:

Background

The digital Clock Drawing Test (dCDT) has been recently used as a more objective tool to assess cognition. However, the association between digitally obtained clock drawing features and structural neuroimaging measures has not been assessed in large population-based studies.

Objective

We aimed to investigate the association between dCDT features and brain volume.

Methods

This study included participants from the Framingham Heart Study who had both a dCDT and magnetic resonance imaging (MRI) scan, and were free of dementia or stroke. Linear regression models were used to assess the association between 18 dCDT composite scores (derived from 105 dCDT raw features) and brain MRI measures, including total cerebral brain volume (TCBV), cerebral white matter volum

SUBMITTER: Yuan J 

PROVIDER: S-EPMC9055470 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature