Effects of aerobic exercise on quality of life of people with HIV-associated neurocognitive disorder on antiretroviral therapy: a randomised controlled trial.

ABSTRACT:

Background

HIV-associated neurocognitive disorder (HAND) negatively impacts quality of life (QoL) of people living with HIV who are on antiretroviral therapy (ART). Behavioural intervention adjunct to ART may improve QoL of people with HAND. We determine the effect of a 12-week aerobic exercise programme on QoL in people with HAND who were receiving ART.

Trial design

This was a parallel-group, randomised controlled trial with concealed allocation and intention-to-treat analysis.

Methods

We identified 73 participants diagnosed with HAND. Participants were sampled from an earlier study that examined the prevalence of HAND according to the Frascati criteria. Participants were randomised and allocated to an intervention of 12-weeks of aerobic exercise, comprising three 20

SUBMITTER: Nweke M 

PROVIDER: S-EPMC9055763 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature