Direct access to multi-functionalized benzenes via [4 + 2] annulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes.

ABSTRACT: An efficient [4 + 2] benzannulation of α-cyano-β-methylenones and α,β-unsaturated aldehydes was achieved under metal-free reaction conditions selectively delivering a wide range of polyfunctional benzenes in high yields respectively (up to 94% yield).

SUBMITTER: Jia Q 

PROVIDER: S-EPMC9055964 | biostudies-literature | 2020 Aug

REPOSITORIES: biostudies-literature