Association of Septic Shock with Mortality in Hospitalized COVID-19 Patients in Wuhan, China.

ABSTRACT:

Purpose

Septic shock is a severe complication of COVID-19 patients. We aim to identify risk factors associated with septic shock and mortality among COVID-19 patients.

Methods

A total of 212 COVID-19 confirmed patients in Wuhan were included in this retrospective study. Clinical outcomes were designated as nonseptic shock and septic shock. Log-rank test was conducted to determine any association with clinical progression. A prediction model was established using random forest.

Results

The mortality of septic shock and nonshock patients with COVID-19 was 96.7% (29/30) and 3.8% (7/182). Patients taking hypnotics had a much lower chance to develop septic shock (HR = 0.096, p=0.0014). By univariate logistic regression analysis, 40 risk factors were significantly as

SUBMITTER: Chen S 

PROVIDER: S-EPMC9056262 | biostudies-literature | 2022

REPOSITORIES: biostudies-literature