Opioid-Induced Constipation: Cost Impact of Approved Medications in the Emergency Department.

ABSTRACT:

Introduction

Opioid-induced constipation (OIC) prescription medications (OIC-Rx) like methylnaltrexone subcutaneous (SC) have shown efficacy in treating OIC in the emergency department (ED). This study aimed to describe and compare healthcare resource utilization (HRU) and healthcare costs in ED patients with OIC receiving OIC-Rx versus those not receiving OIC-Rx.

Methods

Adult patients with OIC during an ED encounter were identified from a hospital-based ED encounters database (2016-2019) and classified on the basis of receipt of OIC-Rx (OIC-Rx versus No OIC-Rx cohorts). Entropy balancing was used to reweight characteristics of the two cohorts. HRU and healthcare costs were measured and compared during the ED encounter and 30-day post-discharge period.

Results

Among

SUBMITTER: Peacock WF 

PROVIDER: S-EPMC9056463 | biostudies-literature | 2022 May

REPOSITORIES: biostudies-literature