Regio- and stereoselective thiocyanatothiolation of alkynes and alkenes by using NH₄SCN and N-thiosuccinimides.

ABSTRACT: A highly regioselective thiocyanatothiolation of alkynes and alkenes assisted by hydrogen bonding under simple and mild conditions is developed. Our thiocyanatothiolation reagents are readily available ammonium thiocyanate and N-thiosuccinimides. This metal-free system offers good chemical yields for a wide range of alkyne and alkene substrates with good functional group tolerance.

SUBMITTER: Qi L 

PROVIDER: S-EPMC9056709 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature