Microencapsulated UV filter@ZIF-8 based sunscreens for broad spectrum UV protection.
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ABSTRACT: Sunscreens play a vital role in protecting human skin from photodamage upon UV exposure, but their effectiveness is limited by degradation and phototoxicity. Photoactivation of UV filters in sunscreen can generate reactive oxygen species, with accompanying cytotoxicity. Herein, we report stable, safe, fluorescent, and long-lasting sunscreens produced by microencapsulation of organic UV filters octylmethoxycinnamate (OMC) and butyl-methoxydibenzoylmethane (BMDM), alone and together, into a microporous zeolitic imidazole framework (ZIF-8). The visibly transparent OMC + BMDM@ZIF-8 sunscreens displayed complete broad-spectrum photoprotection against UV light even after 24 hours. Photostability testing of the sunscreens demonstrated the photo-protective nature of microporous ZIF-8 for stabilizi
SUBMITTER: Sharma A
PROVIDER: S-EPMC9056713 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
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