Ontology highlight
ABSTRACT:
SUBMITTER: Said AI
PROVIDER: S-EPMC9056728 | biostudies-literature | 2020 Sep
REPOSITORIES: biostudies-literature
RSC advances 20200914 56
Reactions of diastereochemically varied norbornene-condensed 2-thioxopyrimidin-4-ones 6 and 10 with variously functionalized hydrazonoyl chlorides 2a-h gave regioselectively angular norbornene-based [1,2,4]triazolo[4,3-<i>a</i>]pyrimidin-7(1<i>H</i>)-ones 7a-h and 11a,c-e, respectively. Thermal retro Diels-Alder (RDA) reaction of 7a-h and 11a,c-e resulted in the target compounds 4a-h as single products. On the other hand, reactions of thiouracil 1 and hydrozonoyl chlorides 2a-e gave regioselecti ...[more]