High-sensitivity SERS based sensing on the labeling side of glass slides using low branched gold nanoparticles prepared with surfactant-free synthesis.

ABSTRACT: Surface-enhanced Raman scattering (SERS) has become a more attractive tool for biological and chemical sensing due to having a great detection potential to extremely low concentrations of analyte. Here, we report high-sensitivity SERS detection of low branched gold nanoparticles which are produced by a surfactant-free synthesis method. The effects of the size and branches of nanoparticles on the SERS signal intensity were also investigated. Among the prepared nanoparticles, a new type of nanoparticle with small protrusions produced by using a very low concentration of silver ions (2 μM in final solution) achieved the best enhancement factor of ∼4 × 10⁵ for DTNB used as a probe molecule. SERS measurements were performed on the labeling side of microscope glass slides for the firs

SUBMITTER: Tezcan T 

PROVIDER: S-EPMC9056777 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature