AuNPs@PMo₁₂ nanozyme: highly oxidase mimetic activity for sensitive and specific colorimetric detection of acetaminophen.

ABSTRACT: The design of a highly specific and sensitive approach for the quantitative and qualitative determination of acetaminophen (AP) is crucial from a human health point of view. In this study, AuNPs@PMo₁₂, as a nanozyme, has been developed for the highly sensitive and selective detection of AP with 3,3',5,5'-tetramethylbenzidine (TMB) within a few seconds without adding oxidizing reagents (e.g. H₂O₂). Synthesized nanosensors are able to oxidize TMB to yellow-brown oxidized TMB (oxTMB). The maximum peak wavelength of oxTMB was observed at 450 nm. The addition of AP and then increasing its concentration led to the production of different products in blue color. In experimental measurements, the limit of detection was obtained as 14.52 mg L^-1. Th

SUBMITTER: Rohani Bastami T 

PROVIDER: S-EPMC9057007 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature