Impact of Bicarbonate Interference on Routine Ion-Selective Electrode Chloride Measurements.

ABSTRACT:

Background

Chloride measurement is crucial for calculating the anion gap. Bicarbonate can interfere with chloride measurements; however, there is no information on the specific types of electrodes affected or the changes in bicarbonate non-selectivity over time. We evaluated the interference of bicarbonate on chloride measurements using different electrodes and the stability of this interference over time.

Methods

The effect of bicarbonate on chloride measured with electrodes of various manufacturers was assessed. When non-selectivity toward bicarbonate was observed, the stability of this interference during the electrode's lifetime was explored. The impact of the bicarbonate concentration on the calibrator was also evaluated.

Results

Non-selectivity was observed for

SUBMITTER: Monteyne T 

PROVIDER: S-EPMC9057815 | biostudies-literature | 2022 Sep

REPOSITORIES: biostudies-literature