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Chronic high-altitude exposure and the epidemiology of ischaemic stroke: a systematic review.


ABSTRACT:

Introduction

About 5.7% of the world population resides above 1500 m. It has been hypothesised that acute exposure to high-altitude locations can increase stroke risk, while chronic hypoxia can reduce stroke-related mortality.

Objective

This review aims to provide an overview of the available evidence on the association between long-term high-altitude exposure and ischaemic stroke.

Design

A systematic review was performed from 1 January 1960 to 1 December 2021 to assess the possible link between high-altitude exposure and ischaemic stroke. The AMED, EMBASE, Cochrane Library, PubMed, MEDLINE, the Europe PubMed Central and the Latin-American bibliographic database Scielo were accessed using the University of Southampton library tool Delphis. In this review, we included

SUBMITTER: Ortiz-Prado E 

PROVIDER: S-EPMC9058702 | biostudies-literature | 2022 Apr

REPOSITORIES: biostudies-literature