Dynamic changes in the pancreatitis activity scoring system during hospital course in a multicenter, prospective cohort.

ABSTRACT:

Background and aim

The primary aim was to validate the Pancreatitis Activity Scoring System (PASS) in a multicenter prospectively ascertained acute pancreatitis (AP) cohort. Second, we investigated the association of early PASS trajectories with disease severity and length of hospital stay (LOS).

Methods

Data were prospectively collected through the APPRENTICE consortium (2015-2018). AP severity was categorized based on revised Atlanta classification. Delta PASS (ΔPASS) was calculated by subtracting activity score from baseline value. PASS trajectories were compared between severity subsets. Subsequently, the cohort was subdivided into three LOS subgroups as short (S-LOS): 2-3 days; intermediate (I-LOS): 3-7 days; and long (L-LOS): ≥7 days. The generalized estimating equatio

SUBMITTER: Paragomi P 

PROVIDER: S-EPMC9058811 | biostudies-literature | 2021 Sep

REPOSITORIES: biostudies-literature